Claes Möller - Institutionen för hälsovetenskaper - Örebro
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Sammanfattning : Müller cells are major glial cells in the retina and have a broad range of functions that Sammanfattning : Müller cells are major glial cells in the retina and have a broad of a retinal progenitor or to maintenance of mature Müller cell functions. 1293, 2005. The optical stretcher: a novel laser tool to micromanipulate cells. J Guck, R Müller cells are living optical fibers in the vertebrate retina. K Franze, J 3D-animering av Müller-cellprocesser (röd) sammankopplade med en retinal microglia- cell (grön).
Stamcells transplantation. Retinal protes Hårcell. Cilie. Müllercell. Fotoreceptorer. Inre segment.
Human neural progenitor cells decrease photoreceptor - DiVA Portal
24 Jan 2020 Amacrine cells, the largest class of inhibitory cell types in the retina, play a critical role in such processing. Müller glia support retinal function.
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In the developed retina, Muller glia provide architectural support and a number of protective and waste-disposal functions. But Dr. Reh has shown that Muller glia can be reprogrammed in a dish to become neurons — cells that are closely related to (A, B) Mu ̈ ller cells pass through the entire retinal tissue, with somata in the INL from which two main trunks pass toward both surfaces of the retina. In the NFL/GCL, the trunks are enlarged Heinrich Müller (1820−1864) in 1851 described the “radial fibers” of the retina which later became known as Müller cells. Müller cells are specialized radial glial cells which span the entire thickness of the neural retina, from the subretinal space to the vitreal surface (Fig. 17.1A, B). In the retina of most vertebrates and even of many mammals, Müller cells are the only type of (macro-) glial cells; thus, they are responsible for a wealth of neuron-supportive functions that, in the brain, rely upon a division of labour among astrocytes, oligodendrocytes, and ependymal cells. Müller glia are the major glial component of the retina.
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Muller cells in the chick retina are generally thought to be a homogeneous population.
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By comparison, Pax2-positive cells are not found within the guinea pig retina; Pax2-expressing glia are confined to the optic nerve. Muller glial cells.€ A: Schema of M€uller glial cell morphology.
2009 Mar 81 Muller JC et al. (2009) Morinda ing retinal ganglion cells in an ocular hypertension model of glaucoma. Exp Neurol.
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Although the morphological features of Müller cells have been extensively studied, their topographic distribution across the retina has not been previously reported. Thus, the molecular regulatory network in the retina not only relies on intracellular signaling pathways but also on extracellular components and cell-cell communications. Muller Glia cells may be a source for a number of additional survival and growth factors like fibroblast growth factor 2 (FGF2). Horizontal cells and other retinal interneuron cells are less likely to be near neighbours of the same subtype than would occur by chance, resulting in ‘exclusion zones’ that separate them. Mosaic arrangements provide a mechanism to distribute each cell type evenly across the retina, ensuring that all parts of the visual field have access to a full set of processing elements.
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Diabetes was induced with streptozotocin. Retinal function was measured Cells in the active Müller cell‐derived clusters then differentiate and generate new neurons for retinal repair, retinal ganglion cells in case of ouabain‐induced cytotoxicity or photoreceptors in case of light damages (Nagashima et al., 2013). Se hela listan på hindawi.com Müller glia cells (MGC), the main type of glia found in the vertebrate retina, can resume proliferation in the rodent adult injured retina but contribute weakly to tissue repair when compared to zebrafish retina. Glial cells of the Retina by Helga Kolb 1. Muller cells.. Muller cells are the principal glial cell of the retina.
The number and density of Müller glia vary between species and their location within the retina (7). For example, in the rabbit retina, Muller glia are most abundant in the central retina where the highest number of neurons is observed. Müller cells are thought to be an essential component of glutamate recycling in the retina (Pow and Robinson, 1994) by importing extracellular glutamate via high-affinity Na + -dependent transporters (e.g.